DSUVIA is used for the management of acute pain, severe enough to require an opioid analgesic and for which alternative treatments are inadequate, in adults. sufentanil is for use in a certify medically supervise healthcare setting, such as hospitals, surgical centers, and emergency departments.
Dosage of DSUVIA is one 30-mcg tablet administer sublingually as need be, with a minimum of 1 hour between doses.
sufentanil allows for a flexible redosing interval that can meet the needs of patients across a range of demographics. Including weight and age. SHOP NOW!
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The maximum cumulative daily dose of DSUVIA is 360 mcg or 12 tablets (12 tablets x 30 mcg/dose).
The safety of sufentanil demonstrated across a range of patients in multiple clinical studies
A total of 646 patients were followed in controlled and uncontrolled studies of DSUVIA or equivalent doses of sublingual sufentanil. The largest controlled study of sufentanil was the abdominal surgery pivotal trial (N=161).
DSUVIA contains sufentanil, a Schedule II control substance. As an opioid, sufentanil exposes users to the risks of addiction, abuse, and misuse.
Profound sedation, respiratory depression, coma, and death may result from the concomitant use of sufentanil with benzodiazepines or other CNS depressants. Because of these risks, reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate.
Management of respiratory depression may include close observation, supportive measures, and use of opioid antagonists, depending on the patient’s clinical status.
Presentation and symptoms are non-specific and include nausea, vomiting, anorexia, fatigue, weakness, dizziness and low blood pressure.
Limitations of Use of DSUVIA
Not for home use or for use in children.
Discontinue treatment with sufentanil before patients leave the certified medically supervised healthcare setting.
Not for use for more than 72 hours.
Only administered by a healthcare provider.
Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses.
Reserve sufentanil for use in patients for whom alternative treatment options.
Provide adequate analgesia, or are not expected to provide adequate analgesia.
Use of DSUVIA
Significant respiratory depression
Acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment
Known or suspect gastrointestinal obstruction, including paralytic ileus
Known hypersensitivity to sufentanil or components of DSUVIA.
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